Jordan Lane, co-founder and CSO for Ignota Labs, breaks down the scientific and structural barriers that contribute to high drug failure rates and explores how artificial intelligence (AI) may help to address them.
The question posed: Why do drugs fail? My response: given the complexity, how has anything ever been approved?! Drug discovery is a game of assumptions and models of models, and it is hoped that everything will translate at a certain point. Drugs fail at all points in this journey when there is a mismatch in those things.
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‘Why drugs fail: the unrelenting challenge of finding a new drug’ can be read in full at Pharmaphorum.
Authored by: Jordan Lane
Published: 5 December 2024 by Pharmaphorum
